Acceptability Model
2017 - 2019
The goal of the Acceptability model project was to propose a new model of protein evolution based on the assumption that the propensity for each amino acid at a site changes over time. Most previous models either required the amino acid propensities to be unchanging with time or to only change at specific points on the tree. Although it is much more difficult to design and test a model that changes continuously, that was precisely the goal of this project.